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Lattice : Human Cell Atlas

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Lattice Wheel

Lattice is the Data Coordination Center for the Chan Zuckerberg Initiative (CZI) Seed Networks, Pediatric Networks, and Ancestry Networks, components of the international Human Cell Atlas consortium.

“The Seed Networks for the Human Cell Atlas projects bring together experimental scientists, computational biologists, software engineers, and physicians to support the continued development of the Human Cell Atlas (HCA), an international effort to map all cells in the human body as a resource for better understanding health and disease.” - Human Cell Atlas Seed Networks

The Lattice team collaborates with researchers to represent sample acquisition, experimental procedures, and data processing steps in structured metadata. We wrangle metadata, raw data, and analysis outputs into the Lattice database which provides contributors the opportunity for intra- and inter-Network data sharing prior to data release.

As stewards for the Seed, Pediatric and Ancestry Network data, the Lattice team actively seeks out opportunities to maximize the value of the data through enhanced findability and reuse. We collaborate with other single-cell data centers to migrate the standardized data corpus from the Lattice database to their open data resources, allowing for data to be easily integrated with community tools and data collections.

Lattice Info Diagram

Lattice is also the Lead Curation Team for the CZ CELLxGENE Discover Portal, a CZI supported single cell research and publication tool.

Lattice work with CELLxGENE developers and computational biologists at the Chan Zuckerberg Initiative to develop a cell-based schema that captures and standardizes key biological and technical variables that impact single-cell data.

We facilitate the submission of data as a means to enhance the data sharing and exploration of each dataset, individually, while ensuring a harmonized data corpus that can be readily searched, filtered, and integrated.

To learn more about Lattice see:
Contact the Lattice team at

Lattice is funded by the Chan Zuckerberg Initiative (CZI).
Lattice logo created by Idan Gabdank, Ph.D.

CZI Single-cell Biology